Barberry (Berberis) berries on a branch

Buying berberine in bulk: extract powder, capsules and private label

Short answer: GOA Supply sells berberine in two bulk forms: berberine extract powder in 10, 50 or 100 kg, and ready-filled berberine capsules in vegetarian HPMC capsules in 20,000, 50,000 or 100,000 pieces. Both are also available as private label. Berberine is a yellow plant alkaloid that occurs in barberry (Berberis) and several other plants. Before you buy, check the botanical source and berberine content on the specification, and the national rules in your sales countries: France, for example, sets a maximum of 380 mg berberine per daily dose and requires label warnings.

What is berberine?

Berberine is a bright yellow alkaloid from the protoberberine group. It occurs mainly in the roots and bark of plants such as Indian barberry (Berberis aristata), common barberry (Berberis vulgaris), goldthread (Coptis) and the bark of Phellodendron species. To make an extract, manufacturers extract the plant material and purify the alkaloid into a fine yellow powder. On the ingredient market, berberine is often traded as a salt, berberine hydrochloride (berberine HCl); the French Compl'Alim database lists this form as a separate ingredient.

For a buyer this means that "berberine" on a price list says little on its own. Two lots with the same name can differ in plant source, salt form and berberine content, so the specification is the document that counts.

Berberine in bulk: the forms at a glance

Form Specification (GOA data) Order quantities Typical business use
Berberine extract powder Yellow powder; berberine content and botanical source on the product specification, available on request 10 / 50 / 100 kg Raw material for capsule fillers, tablet producers and contract manufacturers
Berberine capsules Berberine in vegetarian HPMC capsules; HS code 210690; CoA downloadable on the product page 20,000 / 50,000 / 100,000 capsules Ready-filled capsules for supplement brands, webshops and pharmacies that pack and label themselves

Smaller quantities than these tiers are possible on request. The 50 and 100 kg tiers and the 50,000 and 100,000 capsule tiers come with a volume discount, which you can see per product.

Extract powder or capsules?

Choose the extract powder if you fill your own capsules or tablets, or if a contract manufacturer combines berberine with other ingredients in one formula. You then set the amount per capsule yourself, which matters because national limits are expressed per daily dose. Choose the capsules if you want to start selling without your own filling line: we supply them ready-filled in bulk, and you pack them into your own jars or pouches with your own label. The capsules are filled by a contract manufacturer in the Netherlands.

What to check when you buy berberine wholesale

  • Botanical source and plant part. Ask which plant and part the berberine comes from. The source matters for regulatory status: the EU Novel Food Catalogue, for example, lists the bark of Phellodendron chinense as a novel food that is not yet authorised.
  • Form and content. Ask whether the material is berberine HCl or another form, which minimum berberine content the specification guarantees, and which test method the CoA uses.
  • Dose per capsule. Work out the berberine amount per daily dose of your finished product before you order, so that it fits the rules of every country where you sell.
  • Contaminants. For plant extracts, ask for results on heavy metals, pesticides and microbiology, and for residual solvents if the extraction used solvents.
  • Storage. Store the powder closed, cool, dry and away from light, and reseal opened bags well.

Our checklist for buying supplements in bulk covers the general documents in more detail.

Berberine regulations in the EU

There is no EU-wide maximum for berberine in food supplements yet, but the topic is under review. The European Commission asked EFSA to assess the safety of plant preparations containing berberine under Article 8 of Regulation (EC) No 1925/2006. EFSA's draft opinion was endorsed on 29 January 2026 and was open for public consultation from 3 March to 11 May 2026. In that draft, EFSA concluded that the available data did not allow a safe intake to be established. Check the status of the final opinion and any follow-up by the Commission before you build long-term stock.

National rules already differ. In France, the Compl'Alim database allows berberine hydrochloride and berberine-containing plants such as Berberis vulgaris and Berberis aristata, with a maximum of 380 mg berberine per daily dose. The quantity must be declared, and the label must carry a warning for the risk groups named by the French food safety agency ANSES, such as pregnant and breastfeeding women, children and adolescents. The EU Novel Food Catalogue has no entry for berberine as a substance, so always check the source plant as well.

Private label berberine

For private label we supply the powder or the filled capsules in bulk for your own packaging and labelling. As the brand owner, you arrange the rest:

  • the label, including the mandatory food supplement information and any national warnings;
  • claims, which must comply with Regulation (EC) No 1924/2006;
  • notification where required: none in the Netherlands, a notification via FOODSUP in Belgium, a declaration via Compl'Alim in France and a notification to the BVL in Germany.

Read more on our private label page.

Ordering berberine in bulk

Prices exclude VAT and shipping, and we can arrange transport to your address. Orders are usually shipped within 1–2 weeks, depending on stock. The product specification and a certificate of analysis (CoA) are available on request. See all order options on our wholesale page or browse our plant extracts in bulk.

FAQ

Is berberine a novel food in the EU?
The EU Novel Food Catalogue has no entry for berberine as a substance. The status of the source plant still matters: the bark of Phellodendron chinense, for example, is listed as a novel food that is not yet authorised.

How much berberine may a food supplement contain in France?
Compl'Alim sets a maximum of 380 mg berberine per daily dose. The amount must be declared, and the label must carry a warning for risk groups.

Which berberine form do you supply?
The specification of our berberine extract powder, with the form, content and botanical source, is available on request. Check it against your formula before you order.

Can I sell berberine capsules under my own brand?
Yes. We supply berberine capsules in bulk from 20,000 pieces for your own packaging and label. The capsules are filled by a contract manufacturer in the Netherlands.

What is EFSA assessing?
The safety of plant preparations containing berberine used in food supplements, at the request of the European Commission. The draft opinion was in public consultation until 11 May 2026.

Sources

Written by Florian Fermin, co-owner of GOA Supply.

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